ABTC Protocol Status

As of February 22, 2019 at 4:00 PM

Protocol Number Protocol Title Newly or Recurrent Current Phase Protocol Arm/Group Slots Available Slots on Hold Total number of patients enrolled to date Current Status Wait List Est. Next Cohort Start Date
1202 MK-1775 Newly I Combination Dose Cohort 0

0

Arm 1: 15

Arm 2: 24

Combination Dose: 19

CLOSED

NA NA
1202 MK-1775 Recurrent I Intratumoral Drug Distribution 0 0

12

(+1replaced)

CLOSED NA NA
1301 MLN-0128 Recurrent 0

   Part 2   

Groups A and B

0 0

Part 1-Cohort A: 11

Part 1: Cohort B: 5

(+1replaced)

Part 2: 20(+3replaced)

CLOSED

NA

NA
1302 LAPATINIB Recurrent 0 Group A 0 1 (SK) 20 TEMP CLOSED NA NA
1401 TERAMEPROCOL Recurrent HGG 1 Part 1 0 0 6 TEMP CLOSED NA CLOSED FOR AMENDMENT
1403 NT-17 Newly NA

Group A

(Dex≤0.75mg/day)

3 1 (WF) 2

OPEN

NA NA
1403 NT-17 Newly NA

Group B

(Dex>4mg/day)

5 1 (UA) 0 OPEN NA NA
1501 Checkpoint Inhibitors Recurrent I

PartA LAG-3 Mono

PartB LAG-3 Combo

1

3(CC,1UP,UA)

42

(+2replaced)

OPEN

0

NA
1501 Checkpoint inhibitors Recurrent 0 Intratumoral Studies 5 1 (UP) 3 (Anti-CD137) OPEN NA NA
1601

BAL101553

Newly I Dose Escalation 0 0 7 TEMP CLOSED 2 March 2019
1602 PT2385 Recurrent II Stage 1 0

0

24 (+2replaced)

CLOSED

NA NA
1603 GMCI Newly I Cohort 1 + 2 36 0 0 PENDING NA NA
1604 AMG-232 Recurrent 0 Part 1 - Intratumoral PK/PD studies 14 0 6 OPEN NA NA