ABTC Protocol Status

As of May 16, 2019 at 2:30 PM

Protocol Number Protocol Title Newly or Recurrent Current Phase Protocol Arm/Group Slots Available Slots on Hold Total number of patients enrolled to date Current Status Wait List Est. Next Cohort Start Date
1202 MK-1775 Recurrent 0 Microdialysis 3

0

Arm 1: 15

Arm 2: 24

Combination Dose: 19

OPEN AT

HOPKINS

ONLY

NA NA
1301 MLN-0128 Recurrent 0

   Part 2   

Groups A and B

0 0

Part 1-Cohort A: 11

Part 1: Cohort B: 5

(+1replaced)

Part 2: 20(+3replaced)

CLOSED

NA

NA
1302 LAPATINIB Recurrent 0 Group A 0 0 20 (+1 replaced) TEMP CLOSED NA NA
1401 TERAMEPROCOL Recurrent HGG 1 Part 1 0

1(SK)

8 (+1 replaced) TEMP CLOSED (waiting list open) 1(PT) NA
1403 NT-17 Newly NA

Group A

(Dex≤0.75mg/day)

3 0 3

OPEN

NA NA
1403 NT-17 Newly NA

Group B

(Dex>4mg/day)

6 0 0 OPEN NA NA
1501 Checkpoint Inhibitors Recurrent I

PartA LAG-3 Mono

PartB LAG-3 Combo

0

0

47

(+2replaced)

 CLOSED

NA

NA
1501 Checkpoint inhibitors Recurrent 0 Intratumoral Studies 5 0 4 (3Anti-CD137; 1Anti-LAG-3) OPEN NA NA
1601

BAL101553

Newly I Dose Escalation 0 0 8 TEMP CLOSED NA ~6/10/19
1603 GMCI Newly I Cohort 1 + 2 0

0

(+1replaced)

TEMP CLOSED (for data analysis) 0 NA
1604 AMG-232 Recurrent 0 Part 1 - Intratumoral PK/PD studies 10 1(DF) 9 OPEN NA NA