ABTC Protocol Status

As of October 8, 2018 at 12:28 PM

Protocol Number Protocol Title Newly or Recurrent Current Phase Protocol Arm/Group Slots Available Slots on Hold Total number of patients enrolled to date Current Status Wait List Est. Next Cohort Start Date
1202 MK-1775 Newly I Combination Dose Cohort 0

0

Arm 1: 15

Arm 2: 24

Combination Dose: 19

CLOSED

NA NA
1202 MK-1775 Recurrent I Intratumoral Drug Distribution 0 0

12

(+1replaced)

CLOSED NA NA
1301 MLN-0128 Recurrent 0

   Part 2   

Groups A and B

0 0

Part 1-Cohort A: 11

Part 1: Cohort B: 5

(+1replaced)

Part 2: 20(+3replaced)

CLOSED

NA

NA
1302 LAPATINIB Recurrent 0 Group A 0 0 20

CLOSED

NA NA
1401 TERAMEPROCOL Recurrent HGG 1 Part 1 0 1(UP) 5 TEMP CLOSED 3(JH,2UP) NA
1403 NT-17 Newly NA

Group A

(Dex≤0.75mg/day)

6 0 0

PENDING

NA Pending IRB approvals
1403 NT-17 Newly NA

Group B

(Dex<4mg/day)

6 0 0 PENDING NA Pending IRB approvals
1501 Checkpoint Inhibitors Recurrent I

PartA LAG-3 Mono

PartB CD137 Combo

PartB LAG-3 Combo

4

2(CC)

35

(+2replaced)

OPEN

NA

NA
1501 Checkpoint inhibitors Recurrent 0 Intratumoral Studies 3 0 3 OPEN NA NA
1601

BAL101553

Newly I Dose Escalation 2 2(WF,HF) 3 OPEN NA NA
1602 PT2385 Recurrent II Stage 1 0

0

24 (+2replaced)

CLOSED

NA NA
1603 GMCI Newly I Cohort 1 + 2 36 0 0 PENDING NA NA
1604 AMG-232 Recurrent 0 Part 1 - Intratumoral PK/PD studies (24) 0 2 PENDING REACTIVATION NA NA